解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A key issue relating to developing multi-component anti-malarial vaccines, lies in studying Plasmodium vivax surface proteins' genetic variation. The present work was aimed at amplifying, cloning and sequencing the gene encoding P. vivax merozoite surface protein 5 (PvMSP5) in samples obtained from infected patients f...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006001168
更新日期:2006-12-01 00:00:00
abstract::Currently available methods for the diagnosis of human schistosomiasis often lack enough sensitivity and specificity. Recently, several authors have developed more specific and sensitive diagnostic methods, mainly based on the polymerase chain reaction (PCR) technique. Nevertheless, these have been only applied for th...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000898
更新日期:2006-11-01 00:00:00
abstract::Sodium fluoride (NaF) is an anion that has been previously shown to block the moulting process of Ascaris suum larvae. This study describes moulting and development-specific protein expression profiles of A. suum lung-stage L3 (AsLL3) following NaF exposure. AsLL3s cultured in the presence or absence of NaF were prepa...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000576
更新日期:2006-10-01 00:00:00
abstract::Schistosoma mansoni eggs, miracidia and primary sporocysts were labelled with phalloidin-rhodamine to visualize filamentous actin structures. Analysis of these forms by confocal fluorescence microscopy revealed the presence of previously well-defined circular and longitudinal muscle layers. Besides these muscular laye...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000400
更新日期:2006-09-01 00:00:00
abstract::Transmission experiments were conducted to compare the transmissibility of genetically different Trypanosoma congolense (Savannah subgroup) strains isolated from cattle in a trypanosomiasis endemic area of eastern Zambia. A total of 17 strains were compared. Three strains were extremely virulent with a short pre-paten...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000369
更新日期:2006-09-01 00:00:00
abstract::The understanding of the patterns and processes underlying the structure of parasite communities has progressed significantly in the last years; however, much of the evidence available to date on parasite community comes from unconfirmed studies. In this study the ectoparasite communities of 2 related rockfishes, Seba...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000370
更新日期:2006-09-01 00:00:00
abstract::Asparaginyl proteinases (or legumains) are a recently identified, novel class of cysteine proteinase which specifically hydrolyse peptide bonds after asparagine residues. Legumains have been implicated in the activation of cysteine proteases, particularly cathepsin B-like proteinases which are thought to help degrade ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000229
更新日期:2006-08-01 00:00:00
abstract::A molecular approach was used to genetically characterize 5 species (Aoruroides queenslandensis, Blattophila sphaerolaima, Cordonicola gibsoni, Desmicola ornata and Leidynemella fusiformis) belonging to the superfamily Thelastomatoidea (Nematoda: Oxyurida), a group of pinworms that parasitizes terrestrial arthropods. ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006009978
更新日期:2006-07-01 00:00:00
abstract::Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L. loa are co-endemic. In order to identify factors, including co-infections, which may ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118200600984X
更新日期:2006-06-01 00:00:00
abstract::Parasites often induce behavioural changes in their host. However, it is not necessarily easy to determine whether these changes are representative of an adaptation of the parasite (parasite manipulation), an adaptive response of the host or a side-effect of infection. In a solitary parasitoid of Drosophila larvae (Le...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006009930
更新日期:2006-06-01 00:00:00
abstract::Toxocariasis is a common helminthic infection that has a worldwide distribution. However, data from Lebanon about the prevalence of this infection are non-existent. We conducted a Toxocara seroprevalence study with 150 subjects attending the outpatient clinics at the American University of Beirut Medical Center betwee...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005009637
更新日期:2006-05-01 00:00:00
abstract::The anthelmintic properties of tanniferous plants and of their secondary metabolites represent one possible alternative to chemotherapy that is currently being explored as a means of achieving sustainable control of gastrointestinal nematodes in ruminants. Previous in vivo and in vitro results suggest that tanniferous...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005009509
更新日期:2006-04-01 00:00:00
abstract::Tubulin is the predominant phosphoprotein in Trypanosoma cruzi epimastigotes and is phosphorylated by a protein kinase CK2. Interestingly, the presence or absence of divalent cations affected the solubilization of a pool of the parasite tubulin and the CK2 responsible for its phosphorylation. This fraction of tubulin ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005009352
更新日期:2006-04-01 00:00:00
abstract::Toxoplasma gondii is an obligate intracellular protozoan parasite. The objective of the present study was to examine the behaviour of Toxoplasma gondii RH Ankara strain tachyzoites in a cell culture environment. The study represents the first step in determining whether T. gondii RH Ankara strain tachyzoites, grown in...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005009078
更新日期:2006-03-01 00:00:00
abstract::SSU ribosomal sequences of trypanosomes from Brazilian cattle and water buffalo were used to infer phylogenetic relationships between non-pathogenic T. theileri and allied species parasitic in artiodactyls. T. theileri trypanosomes from distinct geographical regions in Brazil and from other countries were tightly clus...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008929
更新日期:2006-02-01 00:00:00
abstract::Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. While improved sanitation could lead to the eradication of this disease, it is unlikely that this will occur worldwide in the foreseeable future; thus alternative mea...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S003118200600182X
更新日期:2006-01-01 00:00:00
abstract::We have cloned a cDNA encoding a novel antigen from a Sarcoptes scabiei (Acari) cDNA library by immunoscreening with sera from S. scabiei-infected dogs. The antigen is encoded by a 2,157 bp mRNA with a predicted open reading frame of 719 amino acids (molecular weight 79 kDa). Our sequence analysis identified the prese...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008747
更新日期:2006-01-01 00:00:00
abstract::Multiple infections, those by more than one parasite in the same erythrocyte, may be adaptive for the malarial parasite as a means to ensure fertility. Alternatively they may simply be the consequence of a non-adaptive process forcing several parasites to compete for resources in one host cell. Avian hosts infected wi...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008711
更新日期:2006-01-01 00:00:00
abstract::Cyst fluid (CF) of Taenia solium metacestode (TsM) is an important source of serodiagnostic antigens. We have investigated the molecular characteristics of the 120 kDa protein complex in TsM CF purified by fast performance liquid chromatography. The structure of the purified protein was characterized by a variety of p...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008504
更新日期:2005-12-01 00:00:00
abstract::An immunochromatographic test (ICT), using recombinant truncated P50 (P50t), for the detection of antibodies to Babesia gibsoni was developed and evaluated. Whereas all sera from specific pathogen-free dogs were clearly negative, all sera from dogs experimentally infected with B. gibsoni were clearly positive in the I...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008401
更新日期:2005-12-01 00:00:00
abstract::Populations of hosts vary extensively in the types and numbers of parasites that the average individual contains. Understanding the factors that lead to this variation is an important goal for parasite ecologists. We characterized patterns of helminth component community structure in whitefish collected from a cluster...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008371
更新日期:2005-11-01 00:00:00
abstract::Population genetics of multi-host pathogens offers great potential for the understanding of their complex epidemiology but care must be taken to ensure that the sampling procedure does not bias estimates of population indices. The transfer of material to laboratory passage, in particular, runs the risk of bottleneckin...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008413
更新日期:2005-11-01 00:00:00
abstract::West-central China is an important endemic focus of both alveolar and cystic echinococcosis where several species of intermediate host are commonly infected with Echinococcus granulosus and E. multilocularis . Isolates of E. granulosus were collected from humans and other animals from different geographical areas of Q...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005007973
更新日期:2005-10-01 00:00:00
abstract::Malaria remains a major cause of human morbidity and mortality worldwide. Plasmodium falciparum, the most virulent of the 4 human Plasmodium species causing malaria, is potentially life threatening, is increasing in prevalence and is becoming even more resistant to in-use drugs. In light of the growing problem of mult...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005008267
更新日期:2005-10-01 00:00:00
abstract::Strongyloides ratti is a parasitic nematode of rats. The host immune response against S. ratti affects the development of its free-living generation, favouring the development of free-living adult males and females at the expense of directly developing, infective 3rd-stage larvae. However, how the host immune response...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182005007675
更新日期:2005-09-01 00:00:00
abstract::Many different drug-resistant lines of rodent malaria are available as screening models. It is obligatory to screen new compounds for antimalarial activity against a series of resistant lines in order to identify a compound with potential for the treatment of multi-drug resistant (MDR) malaria infections. Instead of u...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200500778x
更新日期:2005-09-01 00:00:00
abstract::The relationships between populations of the Deer Mouse (Peromyscus maniculatus) and the White-footed Mouse (P. leucopus) and their respective Cuterebra parasites were examined. Population genetic structure of hosts and parasites was inferred using cytochrome oxidase mitochondrial sequences of specimens from 7 populat...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182005007584
更新日期:2005-08-01 00:00:00
abstract::A serine protease was purified 942-fold from culture supernatant of L. amazonensis promastigotes using (NH4)2SO4 precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%. The molecular mass of the active enzyme estimate...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006675
更新日期:2005-07-01 00:00:00
abstract::Host nutrition plays an important role in determining the development and success of parasitic infections. While studies of vertebrate hosts are accumulating, little is known about how host nutrition affects parasites of invertebrate hosts. Crithidia bombi is a gut trypanosome parasite of the bumble bee, Bombus terres...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182005007304
更新日期:2005-06-01 00:00:00
abstract::The host-parasite relationship is exquisitely specific. In exploiting the host niche, a variety of helminth parasites have been shown to directly manipulate their hosts' immune responses. We assessed the ability of a whole-worm extract of Hymenolepis diminuta to modulate immune cell activation. Immune cells isolated f...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006985
更新日期:2005-05-01 00:00:00
abstract::Murine monoclonal antibodies (mAbs) against Neospora caninum tachyzoites were produced to identify the cross-reactive antigens between N. caninum and Toxoplasma gondii. Ten mAbs recognizing cross-reactive antigens of both parasites were obtained and tentatively classified into 6 different groups based on their reactiv...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006948
更新日期:2005-05-01 00:00:00
abstract::Cystic echinococcosis (CE) is a high prevalence zoonosis among the rural population of Tacuarembó (Uruguay). The correlation between serological data and the incidence of risk factors was studied in a survey carried out in 1998 among rural communities where 480 individuals were examined by means of abdominal sonograph...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006717
更新日期:2005-04-01 00:00:00
abstract::While purine transport has been widely studied in protozoa, almost nothing is known about their capacity to salvage pyrimidines. Here, we report a Leishmania major transporter with high affinity for uracil (Km=0.32+/-0.07 microM) which we designated LmU1. This transporter displayed a high degree of specificity, as it ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006626
更新日期:2005-03-01 00:00:00
abstract::We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus. Within a 2 h incubation period, all the cysteine proteinases, with the exceptio...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006225
更新日期:2005-02-01 00:00:00
abstract::The flatworm nervous system employs a wide repertoire of neuroactive substances, including small chemical messengers, the so called classical transmitters, and several types of neuropeptides. A large body of research accumulated over four decades has provided a wealth of information on the tissue localization and effe...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182005008565
更新日期:2005-01-01 00:00:00
abstract::In this study, we describe the molecular analysis of zinc-metalloproteases from the abomasal nematode Ostertagia ostertagi which were exclusively recognized by local antibodies of immune cattle. Full-length or partial coding sequences of 4 different zinc-metalloprotease cDNAs of Ostertagia (met-1, -2, -3 and -4) were ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006274
更新日期:2005-01-01 00:00:00
abstract::The dynamic interaction of cells of the immune system with other cells, antigens and secreted factors determines the nature of an immune response. The response of individual cells is governed by the sequence of intracellular signalling events triggered following the association of cell surface molecules during cell-ce...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182005008115
更新日期:2005-01-01 00:00:00
abstract::Due to the low informative value of available morphological characters, cytogenetic and molecular methods, based on rDNA sequencing, were used to characterize adult and larval stages of Phyllodistomum spp. Species studied have 18 chromosomes with comparable absolute and relative lengths. Conventional Giemsa staining a...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006109
更新日期:2004-12-01 00:00:00
abstract::We present a new phylogenetic analysis of 15 primate Plasmodium species based on 18S rDNA sequences including new sequences of Plasmodium coatneyi, P. fieldi, P. gonderi, P. hylobati and P. simium. The results are discussed in the context of the parasite host species and their geographical distribution. Contrary to ot...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004006146
更新日期:2004-12-01 00:00:00
abstract::Phylogenetic relationships among Trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. The phylogenetic trees indicated that the subgenus Herpetosoma is polyphyletic and strongly supporte...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182004005931
更新日期:2004-11-01 00:00:00